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KMID : 1161220230660080339
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Clinical and Experimental Pediatrics
2023 Volume.66 No. 8 p.339 ~ p.347
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Trends of vitamin D in asthma in the pediatric population for two decades: a systematic review
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Sung Myong-Soon
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Abstract
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Vitamin D exhibits anti-inflammatory properties throughmultiple mechanisms. Vitamin D deficiency is associated withincreased inflammation, exacerbations, and overall worseoutcomes in pediatric asthma and is observed in asthmaticchildren with obesity. In addition, given the increase in theprevalence of asthma over the last few decades, there has beenenormous interest in vitamin D supplementation as a potentialtherapeutic option. However, recent studies have suggested nostrong association between vitamin D levels or supplementationand childhood asthma. Recent studies have reported thatobesity and vitamin D deficiency are associated with increasedasthma symptoms. Thus, this review summarizes the findingsof clinical trials regarding the role of vitamin D in pediatricasthma and analyzes the study trends of vitamin D over the past2 decades.
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KEYWORD
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Vitamin D, Asthma, Clinical trials, Child, Obesity
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